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    Drug Information
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    What is Metolazone used for?

    Metolazone is a water pill used to reduce the fluid retention (edema) and swelling caused by conditions such as congestive heart failure or kidney disease. This drug removes excess fluid in the body by increasing the production of urine. Metolazone is also used alone or along with other medications to treat high blood pressure (hypertension). Lowering high blood pressure levels reduces the risk of kidney problems, strokes and heart attacks. Metolazone belongs to a class of medications called diuretics. This medicine may also be used to treat other conditions as determined by your doctor.

    What is the recommended dosage of Metolazone?

    The dosage of Metolazone prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.

    Metolazone can be taken with or without food. Take it with a glass of water. After taking Metolazone, you will need to urinate more often. So do not take your dose close to bedtime.

    What if you miss a dose of Metolazone?

    If your physician has instructed or directed you to take Metolazone medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.

    What if you overdose on Metolazone?

    Any medication taken in excess can have serious consequences. If you suspect an overdose of Metolazone, seek medical attention immediately. Overdose symptoms of Metolazone may include dry mouth, dizziness, drowsiness, coma or irregular heartbeat.

    What other drugs could interact with Metolazone?

    It may be noted that drugs other than those listed above may also interact with Metolazone.

    Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications, over-the-counter medicines that may increase the effect of Metolazone, and dietary supplements like vitamins, minerals and herbal, so that the doctor can warn you of any possible drug interactions.

    Metolazone can interact with ACE inhibitors, nonsteroidal anti-inflammatory drugs, antipsychotics, antineoplastic agents and other diuretics.

    Do let your doctor know if you smoke, consume alcohol or caffeinated drinks, or use illegal drugs as these may interfere with the action of your medication. Make sure to inform your doctor of any medical conditions you may have, or any family history of medical problems. Do not start or stop using any medicine without consulting your doctor.

    What are the side effects of Metolazone?

    Like other medicines, Metolazone can cause some side effects. If they do occur, the side effects of Metolazone are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.

    It is pertinent to note that side effects of Metolazone cannot be anticipated. If any side effects of Metolazone develop or change in intensity, the doctor should be informed as soon as possible.

    Metolazone can cause side effects such as headache, constipation, diarrhea, abdominal pain, loss of appetite, dizziness, lightheadedness, restlessness, muscle pain or cramps. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Metolazone.

    What are the questions to ask your doctor before taking Metolazone?

    Is it possible for me to take Metolazone with other drugs?
    Should certain beverages, foods and other products be avoided when I take Metolazone?
    What are the possible drug interactions of Metolazone?
    How will Metolazone work in my body?
    How should Metolazone be taken?
    How to reduce the risk of Metolazone drug interactions and side effects?


    The health and medical information provided here is intended to supplement and not substitute for the expertise and judgment of your physician, pharmacists or other health care professional. It should not be understood to indicate that the use of Metolazone is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.


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